Ayurgenomics Research
AIRMA explores the emerging interdisciplinary field of Ayurgenomics by integrating Ayurveda, genetics, genomics, neuroscience and systems biology to better understand individual variability, disease susceptibility and personalized healthcare approaches.
Our Ayurgenomics initiatives aim to investigate the molecular and genetic basis of traditional Ayurvedic concepts including Prakriti, neurocognitive variability, metabolic patterns and constitutional susceptibility using modern computational and bioinformatics methodologies.
The organization is presently engaged in conceptual research development, computational analysis and scientific manuscript preparation in multiple areas related to genetics, epigenetics, pharmacogenomics and neurogenomics.
Ongoing Research Projects
- The Genetic Basis of “Vata Prakriti” and Vulnerability to Neuro-Catabolic Diseases
Project Focus:
Investigating possible relationships between Vata-associated genetic markers and susceptibility to neurodegenerative disorders including ALS and Huntington’s disease.
Research Areas:
- Prakriti genetics
- Neurodegeneration
- SNP analysis
- Ayurgenomics
Status: Ongoing (Searching for Funds)
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- Identifying Pharmacogenomic Variations in “Pitta” Phenotypes Regarding Response to Neuro-Stimulants
Project Focus:
Studying variations in metabolic and drug-processing genes associated with Pitta phenotypes and their potential influence on neuro-stimulant responses.
Research Areas:
- Pharmacogenomics
- Personalized medicine
- CYP450 pathway analysis
- Neuropharmacology
Status: Ongoing (Searching for Funds)
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- Mapping “Medhya Rasayana” Herbs to the Epigenetic Landscape of Neurodegenerative Diseases
Project Focus:
Exploring the epigenetic interactions of Ayurvedic nootropic herbs with HDACs, DNMTs and gene regulatory pathways associated with Alzheimer’s and Parkinson’s disease.
Research Areas:
- Epigenetics
- Neurodegeneration
- Ayurvedic nootropics
- Gene expression regulation
Status: Ongoing (Searching for funds)
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- Transcriptomic Meta-Analysis of “Medhya” Herbs on Synaptic Plasticity Genes
Project Focus:
Investigating transcriptomic signatures associated with Ayurvedic Medhya herbs and their influence on neuroplasticity-related genes including BDNF and CREB pathways.
Research Areas:
- Transcriptomics
- RNA-seq analysis
- Neuroplasticity
- Computational biology
Status: Ongoing (Searching for funds)
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- Stress-Induced Epigenetic Regulation: Glucocorticoid Receptor (GR) – Histone Core Complex Warping Under Psychological Cortisol Spikes
Project Focus:
Studying stress-associated epigenetic modulation and structural interactions between glucocorticoid receptors and histone-associated regulatory mechanisms.
Research Areas:
- Stress biology
- Cortisol signalling
- Histone interactions
- Epigenetic regulation
Status: Ongoing (Searching for funds)
All projects are presently under active conceptual investigation and manuscript preparation through AIRMA’s independent interdisciplinary research initiatives.